Thermal ablation devices

For the prevention of cervical cancer in low- and middle-income countries.

Unitaid Executive Board sets vision for the future with approval of five new areas for intervention at 44th session

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Unitaid and Expertise France announce the launch of Phase II of the SUCCESS program for the elimination of cervical cancer in ten low-resource countries

Yaoundé – Unitaid and Expertise France announce the launch of Phase II of the SUCCESS program – Scale Up Cervical Cancer Elimination with Secondary Prevention Strategy, for the elimination of cervical cancer in ten low-resource countries.

Co-funded by Unitaid and Expertise France through L’Initiative, a French facility that complements the Global Fund against AIDS, tuberculosis and malaria, the SUCCESS project aims to reduce morbidity and mortality from cervical cancer through an effective secondary prevention strategy, notably through HPV screening and the treatment of precancerous lesions by thermal ablation for the most vulnerable women, with a priority for women living with HIV.

After a successful first phase that enabled the screening of 182,093 women, 8.2% of whom are living with HIV, in Burkina Faso, Ivory Coast, Guatemala, and the Philippines, SUCCESS 2 is scaling up and will roll out until April 2026 by integrating six new countries: Guinea, Benin, Burundi, Togo, Cameroon, and Ghana.

This innovative project adopts an integrated approach, deploying effective screening and treatment tools, integrating these services into existing healthcare systems, and strengthening awareness and community engagement to increase demand for cervical cancer prevention. By leveraging the lessons from the first phase, SUCCESS 2 aims to extend its impact to contribute significantly to the elimination of cervical cancer on a larger scale.

Dr. Philippe Duneton, Executive Director of Unitaid, emphasized the importance of this program: “Cervical cancer represents a preventable burden. Through an initiative like SUCCESS, we can not only save lives but also pave the way towards the eradication of this disease.”

With a total funding of $35,870,767, the contributions from Unitaid and Expertise France illustrate the importance of international collaboration in developing a secondary prevention model for cervical cancer, and advocating for financial and political support at all levels.

Eric Fleutelot, Technical Director of the Health Department at Expertise France, added: “With SUCCESS 2, and thanks to the support from Unitaid and collaboration with our strategic partners, we are strengthening our commitment to women’s health and the fight against cervical cancer. It is another step towards global equitable health and the elimination of this disease by 2030.”

The SUCCESS 2 program is a promising model of international collaboration, blending innovation and community engagement for women’s health. The project will be implemented in close collaboration with local and international partners to maximize the program’s impact and reach. Jhpiego will operate in Burkina Faso, Ivory Coast, the Philippines, and Guatemala. Médecins du Monde will support efforts in Ivory Coast, Solthis in Guinea, the National Cancer Control Program (PNLCa) will act in Ivory Coast, the PNLNMT in Benin, ANSS in Burundi, and PNLS in Togo.


Contacts for the media:

Unitaid | Hervé Verhoosel, Head of Communications and Spokesperson | +33 6 22 59 73 54 | verhooselh@unitaid.who.int

Expertise France | Dr Lisa Peiching Huang, SUCCESS project director | lisa.huang@expertisefrance.fr


About Unitaid

Unitaid saves lives by making new health products available and affordable for people in low- and middle-income countries. Unitaid works with partners to identify innovative treatments, tests and tools, helps tackle the market barriers that are holding them back, and gets them to the people who need them most – fast. Since it was created in 2006, Unitaid has unlocked access to more than 100 groundbreaking health products to help address the world’s greatest health challenges, including HIV, TB, and malaria; women’s and children’s health; and pandemic prevention, preparedness and response. Every year, these products benefit more than 300 million people. Unitaid is a hosted partnership of the World Health Organization.

For more information: https://unitaid.org

About Expertise France

Expertise France is France’s public agency and interministerial actor in charge of international technical cooperation, the second-largest in Europe. As a subsidiary of Agence Française de Développement Group (AFD Group), it designs and implements projects that sustainably strengthen public policies in developing and emerging countries. Expertise France works in key areas of development: governance, security, climate change, health, education, and more. Alongside its partners, it contributes to achieving the Sustainable Development Goals (SDGs). Know-how in common.

For more information: https://expertisefrance.fr

About L’Initiative

Launched at the end of 2011, L’Initiative is a French facility that complements the Global Fund against AIDS, tuberculosis and malaria. It provides technical assistance and support to catalytic projects in around 40 Global Fund recipient countries to improve the effectiveness of grants and strengthen the health impact of the programs funded. As such, it contributes to ensuring the effectiveness of the response to pandemics.

L’Initiative’s recent evolution has demonstrated its catalytic effect through building the capacity of health stakeholders, including civil society and research organizations, improving institutional, political and social frameworks, supporting innovative approaches to respond to pandemics and strengthening systems for health.

It is implemented by Expertise France, the international technical cooperation agency, and is fully funded by the French Ministry for Europe and Foreign Affairs, which is its supervising body.

For more information: https://linitiative.expertisefrance.fr

Cervical cancer

In advance of International Women’s Day, Unitaid Board Chair calls for urgent action to advance access to cervical cancer prevention for women in resource-limited settings

Few areas of health hold as much potential to advance the Sustainable Development Goals as an investment in women’s health. Yet gender inequalities deprive women of the opportunities and power to access care, and deprioritize conditions that specifically affect women. Women in low- and middle-income countries face even greater challenges, with limited attention and funding dedicated to addressing health concerns that primarily impact people in these countries.

Cervical cancer is one such example. Despite being highly preventable and curable when women have access to prevention, screening and treatment, some 300,000 women die from cervical cancer every year. 90% of the women who die live in low- or middle-income countries where access to preventive treatment is scarce.

In advance of International Women’s Day (8 March), Marisol Touraine, Unitaid’s Executive Board Chair, called for urgent action to ensure women everywhere have access to the life-saving care that can prevent one of the leading causes of cancer in women.

She delivered her remarks at the opening session of the Cervical Cancer Elimination Forum, a global effort to catalyze national and global momentum to end the preventable disease taking place in Cartagena de Indias, Colombia, from 5-7 March. Governments, donors, multilateral institutions, and partners announced major new policy, programmatic and financial commitments, including nearly US$600 million in new funding, to eliminate cervical cancer.

Co-organizing partners of the Forum include Unitaid, alongside the Governments of Colombia and Spain, the Bill & Melinda Gates Foundation, Gavi, the Vaccine Alliance, the Global Financing Facility, the Pan American Health Organization (PAHO), UNICEF, the United States Agency for International Development (USAID), the World Bank and the World Health Organization.

Ms. Touraine’s remarks are reproduced in full below.

Read more about Unitaid’s work in cervical cancer in our issue brief.


Excellencies,

Dear Colleagues, 

It is a great honor for me to be with you today. As a courtesy, I will now speak Spanish. 

[Translated from Spanish]
Ladies and gentlemen,

Every two minutes, a woman dies of cervical cancer, a disease that we know how to prevent, detect and cure. This reality is shocking.

It is all the more shocking because this disease affects the most disadvantaged women: 90% of women who die from cervical cancer live in low- and middle-income countries, and more than others, it affects women living with HIV.

There is already a vaccine that works with a single injection. We have also proven effective screening and treatment methods. So why aren’t these solutions reaching all those who need them?

No matter how good a treatment may be, its interest is limited if it is not accessible to all. This is why the specific role of Unitaid, the multilateral organization associated with the WHO that I chair, is focused on overcoming the barriers that hinder access to health so that innovations can be brought to everyone, everywhere in the world. Our ambition is to first identify innovative treatments, tests and tools, and then to translate them into concrete solutions for the most vulnerable populations. We are a very pragmatic organization, looking for concrete solutions for people to live and live better. We have worked in the fields of HIV, malaria and tuberculosis with spectacular results. We have brought oxygen where there was none during the COVID-19 pandemic. We developed a climate impact strategy that will allow us to continue saving lives without harming the environment. And of course, maternal and child health is one of our major focuses. The results speak for themselves: 170 million people benefit from our work every year. Since our creation in 2006, we have facilitated access to more than 100 innovative health products.

More specifically, we are the largest funder of innovations to screen and treat cervical precancer in women in low- and middle-income countries. Our work in 14 countries on three continents has developed effective models of secondary prevention and is laying the groundwork for national cervical cancer elimination programs around the world.

We have focused on the need to expand cervical cancer services beyond health facilities and to ensure that tools work in resource-poor settings.

First, we have worked on simple and convenient self-collection methods. The pelvic exam that has traditionally been used to collect a cervical sample can, for reasons ranging from cultural or religious considerations to fear or shame, deter women from testing. Learning from our successful experience in promoting the uptake of HIV self-testing, Unitaid has pioneered self-collection strategies for HPV testing.

Also, Unitaid has contributed to the introduction of simple-to-use, battery-powered, hand-held thermal ablation devices and has achieved price reductions of nearly 50%. Unitaid’s expertise and ability to negotiate prices for medical tools are recognized as unique. In practice, these tools allow treatment to be performed in primary care centers, or even as part of outreach programs, at a quarter of the cost of cryotherapy per woman treated. It is a spectacular program, which makes us proud because women and nurses tell us that it has changed their lives.

At Unitaid, we know that actions in the direction of women cannot be done without their participation. We are willing to work with them, with their communities, because a disease is part of a more global situation. So, to cure well, we need a global social and economic vision.

Just two years after the launch of WHO’s elimination strategy, Unitaid had already implemented models that successfully met WHO’s goal of providing treatment to 90% of women identified with precancerous cervical cells.

Between 2019 and 2023, our programs reached approximately 1.5 million women on three continents, trained tens of thousands of health workers and greatly expanded the number of health centers offering life-saving screening, detection and preventive treatment.

You can now understand how, at Unitaid, we are convinced that the international community has the conditions in place to end the scourge of cervical cancer. For our part, we are committed to supporting countries and the international community in the implementation and deployment of these solutions. We will also continue to seek solutions that are even more appropriate and affordable. But to deliver on the promises of these tools, we need everyone.

The time has come for governments and international organizations to fulfill the promises made for solutions whose effectiveness has already been demonstrated and proven. Today more than ever we need strong political will. First, so that countries can massively deploy our cervical precancer elimination program.

I also want to insist that the elimination of this cancer requires a holistic approach, consisting not only of primary prevention, but also the fundamental role of secondary screening and treatment.

Of course, the HPV vaccine represents a fantastic hope for prevention. But we must also commit to ensuring the widespread availability of effective screening and treatment methods if we are to achieve the elimination of cervical cancer in our lifetimes and extend protection to the millions of women who cannot benefit from the vaccine.

The solutions are already there; let us together honor the promises that are in our hands!

Nearly US$600 million in new funding was committed to advance cervical cancer elimination efforts at the Forum this week.

Read more about Unitaid’s work in cervical cancer in our issue brief.

Cervical Cancer Day of Elimination: Improving preventive services in low- and middle-income countries

Geneva – Cervical cancer is highly preventable when women have access to vaccination, early and effective screening and pre-cancer treatment. However, 90% of cervical cancer deaths occur in low- and middle-income countries, in large part due to a gap in vital preventive services. On Cervical Cancer Elimination Day of Action, Unitaid remains committed to improving equitable access to the tools and strategies that can save lives.

In November 2020, the World Health Organization (WHO) launched its strategy for the elimination of cervical cancer, marking the first time the world has committed to ending a cancer as a public health threat. The strategy is based on achieving three targets by 2030: to reach 90% of girls with the human papillomavirus (HPV) vaccine by the age of 15; to screen 70% of women with a high-performance test twice – at ages 35 and 45; and to treat 90% of women with pre-cancer and manage 90% of all cases of invasive cancer.

Journée internationale des femmes : Réduire les inégalités d’accès aux médicaments vitaux entre les hommes et les femmes