Malaria

Over the past 20 years, remarkable progress has been achieved in the fight against malaria. But this progress is under threat.

75 %

Children under 5 account for three-quarters of all deaths from malaria

608000

In 2022, 608,000 people died from malaria – almost all of them in sub-Saharan Africa

50 %

Nearly half the world’s population is at risk of malaria

249 million

The number of malaria cases worldwide in 2022, significantly higher than before the COVID-19 pandemic

The problem

Vulnerable populations are at highest risk

In the case of malaria, this means children under 5 who account for more than 75% of all deaths. Pregnant women and children under 10 account for nearly all the rest.

Malaria parasites and the mosquitoes that transmit them are becoming resistant to the recommended antimalarial medicines and the insecticides used to repel and kill them, threatening our strongest lines of defense.

The most common type of malaria outside sub-Saharan Africa is a complex and persistent form of the disease that poses a risk to more than one-third of the world’s population.

As temperatures across the world rise, hot and humid areas where mosquitoes thrive are expanding and the transmission season is getting longer, putting more people at risk for longer periods of time. The spread of an invasive mosquito species that can transmit the two malaria parasites that pose the greatest threat to humans is an emerging concern.

Game-changing innovations
Our work ensures the most promising health technologies and interventions reach communities in need as quickly as possible. These are just a few examples of the health tools we are backing.
Seasonal malaria chemoprevention
A preventive strategy that now reaches 49 million children and prevents 100,000 child deaths each year.
Spatial repellents
Vector control tools permeated with slow-release chemicals that hang on the wall and provide protection from mosquitoes indoors.
Next-generation mosquito nets
Protect people against mosquitoes that have developed resistance to conventional insecticides.
World’s first malaria vaccine
With 1.7 million children vaccinated in pilots that provided the evidence to underpin a WHO recommendation for scale up.

Our response

We work with partners to identify emerging challenges and underserved populations. We then invest in cutting-edge technologies and innovative approaches that strengthen the malaria response.