Mosquitoes die quickly after biting humans and livestock treated with the drug
The world is not on track to achieve the goals proposed by WHO in the Global Technical Strategy for Malaria 2016-2030, and available tools are unlikely to suffice. Vector control, the most effective strategy for fighting malaria, is doubly threatened by widespread insecticide resistance and behavioral adaptations that allow mosquitoes to elude treated bed nets and homes treated with long-lasting sprays.
WHO data from 2015–2017 shows no significant progress in reducing global malaria. There were an estimated 219 million cases and 435,000 related deaths in 2017.
ISGlobal’s project, known as BOHEMIA (Broad One Health Endectocide-based Malaria Intervention in Africa), seeks to reduce malaria transmission by killing biting mosquitos. The project will evaluate impact of the mass-distribution of the anti-parasitic drug ivermectin in Tanzania and Mozambique during the rainy season, when malaria is most prevalent.
BOHEMIA complements malaria-preventing tools Unitaid already supports, including insecticide-treated bed nets, long-lasting indoor insecticide sprays, malaria vaccine, and better medicines for treatment and prevention.
The impact we are seeking
The project seeks to collect data on ivermectin’s impact on malaria incidence in humans and animals, mosquito behavior, the economy, environment, and on community acceptance of the drug.