This project led a multi-country effort to improve the quality of treatment for children with HIV, to optimize pediatric antiretroviral drugs and to transition procurement from Unitaid to other buyers. Working in partnership with the Clinton Health Access Initiative (CHAI), we secured long-term agreements with primary and secondary suppliers and negotiated reduced prices. Child HIV medicines are specifically adapted so the youngest and most vulnerable can more easily access treatment. Fruit-flavored formulations make it easier for caregivers to administer treatment, and proper guidance of dosing means children benefit from more effective care. Between 2007 and 2014, the project extended access to HIV treatment for children in 40 countries – and the impact of this work continues to grow as more countries take up child medicines.