Postpartum Hemorrhage

Severe bleeding after childbirth is the leading cause of maternal death. Life-saving medicines and detection tools exist, but are largely unavailable in low- and middle-income countries where nearly all deaths occur.

14 million

Approximately 14 million women hemorrhage during childbirth each year.

94 %

It is estimated that 94% of all maternal deaths occur in low- and middle-income countries.

70000

More than 70,000 women die every year due to severe bleeding after childbirth.

50 %

Close to half of all women with postpartum hemorrhage never get diagnosed.

The problem

Tools aren’t adapted to the realities of low-resource health settings

Medicines for treating postpartum hemorrhage are not suited to needs of women who give birth in low- and middle-income countries. Most births take place at lower levels of the health system, which are often not equipped with highly skilled health care workers, and several important treatments for severe bleeding must be delivered intravenously, which requires specialist training. Meanwhile, there is an overreliance on a drug that requires cold chain storage, which can degrade in quality with that is not maintained. Many other women give birth at home or without medical assistance and need access to medicines that can be self-administered.

Health systems primarily rely on visual estimates of blood loss to judge if a woman’s life may be in danger, which can severely delay access to treatment. Women who give birth at home have limited options to prevent bleeding and may live far from a health center if an emergency occurs.

In many countries there is limited availability of low-cost and quality medicines for preventing and treating severe postpartum bleeding. Drugs adapted to local environmental conditions may also be in short supply.

Game-changing innovations
Heat-stable carbetocin
An alternative to the most widely used drug for treating postpartum hemorrhage that doesn’t require cold chain storage.
Tranexamic acid (TXA)
A WHO-recommended treatment proven to reduce the risk of hemorrhage by one-third.
Misoprostol
A pill that can be self-administered to prevent hemorrhage when giving birth at home.
Drape
A detection device that collects blood during birth and provides a more precise way to identify women needing treatment.

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